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staphylococcus aureus mssa atcc 25923 strain  (ATCC)


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    ATCC staphylococcus aureus mssa atcc 25923 strain
    Staphylococcus Aureus Mssa Atcc 25923 Strain, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 33825 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains <t>ATCC</t> <t>25923</t> <t>(ST243/CC30,</t> <t>CP009361.1),</t> ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.
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    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains <t>ATCC</t> <t>25923</t> <t>(ST243/CC30,</t> <t>CP009361.1),</t> ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.
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    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains <t>ATCC</t> <t>25923</t> <t>(ST243/CC30,</t> <t>CP009361.1),</t> ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.
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    A. MRSA expresses five PBPs, PBP1, PBP2, PBP2A (pink), PBP3, and PBP4. B. FICI values calculated based on MRSA USA300 grown in the presence of BAY 11-7082 and another antibiotic. FICI values <0.5 represent synergy, values between 0.5-4 represent no interaction, and values >4 represent antagonism. C. FICI values for MRSA USA300 (pink) and MSSA <t>ATCC</t> <t>29213</t> (blue) grown in the presence of BAY 11-7082 and a β-lactam that synergizes with BAY 11-7082 in MRSA. Data represent an average of three independent experiments performed in triplicate.
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    A. MRSA expresses five PBPs, PBP1, PBP2, PBP2A (pink), PBP3, and PBP4. B. FICI values calculated based on MRSA USA300 grown in the presence of BAY 11-7082 and another antibiotic. FICI values <0.5 represent synergy, values between 0.5-4 represent no interaction, and values >4 represent antagonism. C. FICI values for MRSA USA300 (pink) and MSSA <t>ATCC</t> <t>29213</t> (blue) grown in the presence of BAY 11-7082 and a β-lactam that synergizes with BAY 11-7082 in MRSA. Data represent an average of three independent experiments performed in triplicate.
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    methicillin susceptible strain atcc 53657 mssa  (ATCC)
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    A. MRSA expresses five PBPs, PBP1, PBP2, PBP2A (pink), PBP3, and PBP4. B. FICI values calculated based on MRSA USA300 grown in the presence of BAY 11-7082 and another antibiotic. FICI values <0.5 represent synergy, values between 0.5-4 represent no interaction, and values >4 represent antagonism. C. FICI values for MRSA USA300 (pink) and MSSA <t>ATCC</t> <t>29213</t> (blue) grown in the presence of BAY 11-7082 and a β-lactam that synergizes with BAY 11-7082 in MRSA. Data represent an average of three independent experiments performed in triplicate.
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    Image Search Results


    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains ATCC 25923 (ST243/CC30, CP009361.1), ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.

    Journal: JAC-Antimicrobial Resistance

    Article Title: Genetic and clinical landscape of methicillin-resistant Staphylococcus aureus isolates lacking the mec gene, in Japan

    doi: 10.1093/jacamr/dlag008

    Figure Lengend Snippet: A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains ATCC 25923 (ST243/CC30, CP009361.1), ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.

    Article Snippet: A comparative analysis of the nucleotide sequences or deduced amino acid sequences extracted from 13 MRLMs with those from the MSSA reference strain ATCC 25923 (ST243/CC30, CP009361.1) was conducted to identify mutations in the pbp4 promoter and amino acid substitutions in PBPs 1-4, GdpP, YjbH and AcrB.

    Techniques: Sequencing

    A. MRSA expresses five PBPs, PBP1, PBP2, PBP2A (pink), PBP3, and PBP4. B. FICI values calculated based on MRSA USA300 grown in the presence of BAY 11-7082 and another antibiotic. FICI values <0.5 represent synergy, values between 0.5-4 represent no interaction, and values >4 represent antagonism. C. FICI values for MRSA USA300 (pink) and MSSA ATCC 29213 (blue) grown in the presence of BAY 11-7082 and a β-lactam that synergizes with BAY 11-7082 in MRSA. Data represent an average of three independent experiments performed in triplicate.

    Journal: bioRxiv

    Article Title: BAY 11-7082 potentiates select β-lactams to inhibit growth of methicillin-resistant Staphylococcus aureus

    doi: 10.64898/2026.01.13.699313

    Figure Lengend Snippet: A. MRSA expresses five PBPs, PBP1, PBP2, PBP2A (pink), PBP3, and PBP4. B. FICI values calculated based on MRSA USA300 grown in the presence of BAY 11-7082 and another antibiotic. FICI values <0.5 represent synergy, values between 0.5-4 represent no interaction, and values >4 represent antagonism. C. FICI values for MRSA USA300 (pink) and MSSA ATCC 29213 (blue) grown in the presence of BAY 11-7082 and a β-lactam that synergizes with BAY 11-7082 in MRSA. Data represent an average of three independent experiments performed in triplicate.

    Article Snippet: We conducted checkerboard assays with MRSA strain USA300, which has mecA ( , Figure S2 ), as well as methicillin-sensitive S. aureus (MSSA) strain ATCC 29213, which does not, to understand the potential role of PBP2a ( , Figure S3 ).

    Techniques: